The general area of my research lies in biomedical imaging, particularly the development and application of magnetic resonance in biomedicine. In this regard, our research involves both magnetic resonance imaging and in vivo magnetic resonance spectroscopy with an emphasis on applying them to the study of the brain. Currently, our work focuses on (1) functional MRI, a methodology for the noninvasive mapping of brain activity, (2) diffusion tensor imaging, which can be used for examining the directionality and integrity of white matter tracts, (3) MRI based molecular imaging, and (4) in vivo magnetic resonance spectroscopy.

I believe the future of imaging lies in non-invasive mapping of function and physiology and in non-invasive phenotyping. Success in this general area will require efforts in technical development, study of animal models and validation in human subjects. This research area holds great commercial potential as it will aid in drug discovery, development of personalized medicine, and genomic research.

Our 9.4T animal MRI/MRS system, which is funded largely by GRA, is providing us with unprecedented sensitivity and resolution for imaging rodents. The reporter gene for MRI that we have recently established is opening up a window for molecular imaging,

I came to Georgia because of the new opportunities presented to me. First, the generous support from GRA and Emory made it possible for me to set up a world class imaging center. Second, even though I was in a well-established magnetic resonance center in Minnesota, I was very attracted by the opportunity to establish a new MR center at Emory. Third, the newly established joint biomedical engineering department was growing rapidly and opened up an opportunity for me to be involved in the growth of a dynamic department and education in biomedical engineering. Last, but not the least, I was attracted by the opportunity to collaborate with many basic and clinical neuroscientists.