Lin Mei, M.D., Ph.D.
Lin Mei investigates synapses, the connections between nerve cells or a nerve and target cell. By learning more about how they’re established and how their function adapts to ever-changing environments, he increases the potential for finding new ways to treat neurological and psychiatric diseases.
Certain proteins in the body’s cells are the focus of Mei’s work. If these proteins are mutated, inactive or missing, the body’s neural function can be impaired. Mei seeks to identify the proteins that may serve as targets to better diagnose and treat muscular dystrophies such as Lou Gehrig’s disease (ALS), congenital myasthenic syndrome and myasthenia gravis.
Mei has also studied susceptibility genes of brain disorders such as schizophrenia, bipolar disorder and autism. Specifically, he has investigated the normal function of the proteins encoded by these susceptibility genes, and pathophysiological mechanisms when the proteins’ function or levels become abnormal.
- Synapse formation and plasticity
- Therapeutic strategies to treat abnormal synaptic structure and function in such diseases as schizophrenia, epilepsy, autism, muscular dystrophy and ALS
Mei came to Georgia to take part in the creative and productive research environment at Georgia Regents University.